UVA engineers and clinicians are not merely creating traditional research partnerships but are forming a new sustainable ecosystem for advancing the future of medical care. From cancer and mobile health, to implantable sensors and patient monitoring, to big data for predictive medicine, researchers are developing ways to remedy cancer caregiver depression and anxiety, detect asthma attacks and predict malnutrition in children of local and global rural communities. The technologies made possible by integrating medicine and engineering, such as seamless mobile health apps, wireless body sensors and machine learning models for health, will transform how we tailor care and target disease.