Profiles of our graduating doctoral and master of science students

Mentoring students as they develop, propose and successfully defend a thesis is among a faculty member's highest honors. Meet our thirteen new PhDs and three master of science graduates, and hear the special messages sent to them by their advisors.

Congratulations, Class of 2021 Graduate Students

Celebrating PhD, MS and ME students in the BME Class of 2021. Direct link on YouTube: https://youtu.be/o9wg042ZdQM

 

Doctoral Students

Laura Caggiano, PhD

  • The Impact of Regional Mechanics and Tissue Structure on Scar Formation Following Myocardial Infarction

    The Impact of Regional Mechanics and Tissue Structure on Scar Formation Following Myocardial Infarction


    Am J Physiol Heart Circ Physiol 2018 Oct 1;315(4):H1041-H1050. Surgical reinforcement alters collagen alignment and turnover in healing myocardial infarcts. Laura R Caggiano, Jia-Jye Lee, Jeffrey W Holmes.

Congratulations, Dr. Caggiano

A special message sent to Laura Cagginao from thesis advisor, Dr. Jeff Holmes.

Bryan Chun, PhD

  • High-Content Imaging Approaches for Studying Single-Cardiomyocyte Pleiotropic Decision-Making

    High-Content Imaging Approaches for Studying Single-Cardiomyocyte Pleiotropic Decision-Making


    Computational model of cardiomyocyte apoptosis identifies mechanisms of tyrosine kinase inhibitor-induced cardiotoxicity. Grabowska ME, Chun B, Moya R, Saucerman JJ. J Mol Cell Cardiol. 2021 Mar 3;155:66-77.

Congratulations, Dr. Chun

A special message for Bryan Chun from thesis Advisor Dr. Jeff Saucerman.

Bonnie Dougherty, PhD

  • Identifying Biomarkers of Cardiotoxicity with a Genome-Scale Model of Metabolism Constrained with 'Omics Data

    Identifying Biomarkers of Cardiotoxicity with a Genome-Scale Model of Metabolism Constrained with 'Omics Data


    Identifying functional metabolic shifts in heart failure with the integration of omics data and a heart-specific, genome-scale model. Dougherty BV, Rawls KD, Kolling GL, Vinnakota KC, Wallqvist A, Papin JA. Cell Rep. 2021 Mar 9;34(10):108836.

Congratulations, Dr. Dougherty

A special message for Bonnie Dougherty from thesis Advisor Dr. Jason Papin.

Laura Dunphy, PhD

  • Systems Analyses for Improved Context-Specific Understanding of Bacterial Infections

    Systems Analyses for Improved Context-Specific Understanding of Bacterial Infections


    Integrated Experimental and Computational Analyses Reveal Differential Metabolic Functionality in Antibiotic-Resistant Pseudomonas aeruginosa. Dunphy LJ, Yen P, Papin JA. Cell Syst. 2019 Jan 23;8(1):3-14.e3.
    Biomedical applications of genome-scale metabolic network reconstructions of human pathogens. Dunphy LJ, Papin JA. Curr Opin Biotechnol. 2018 Jun;51:70-79. doi: 10.1016/j.copbio.2017.11.014. Epub 2017 Dec 7.

Congratulations, Dr. Dunphy

A special message for Laura Dunphy from thesis Advisor Dr. Jason Papin.

Jack Dienes, PhD

  • Rat Gait Biomechanics: Using Kinematics and Kinetics to Evaluate the Effect of Injury and Treatment Efficacy for Volumetric Muscle Loss and Muscle/Nerve Polytrauma

    Rat Gait Biomechanics: Using Kinematics and Kinetics to Evaluate the Effect of Injury and Treatment Efficacy for Volumetric Muscle Loss and Muscle/Nerve Polytrauma


    Semisynthetic Hyaluronic Acid-Based Hydrogel Promotes Recovery of the Injured Tibialis Anterior Skeletal Muscle Form and Function. Dienes J, Browne S, Farjun B, Amaral Passipieri J, Mintz EL, Killian G, Healy KE, Christ GJ. ACS Biomater Sci Eng. 2021 Apr 12;7(4):1587-1599. 
    Analysis and Modeling of Rat Gait Biomechanical Deficits in Response to Volumetric Muscle Loss Injury. Dienes JA, Hu X, Janson KD, Slater C, Dooley EA, Christ GJ, Russell SD. Front Bioeng Biotechnol. 2019 Jun 19;7:146.

Congratulations, Dr. Dienes

A special message for Jack Dienes from thesis Advisor Dr. George Christ.

Katie Knaus, PhD

  • Form and Function Relationships Governing Complex Muscle-Soft Tissue Interactions Revealed with 3D Modeling: Applications to Aging

    Form and Function Relationships Governing Complex Muscle-Soft Tissue Interactions Revealed with 3D Modeling: Applications to Aging


    The action of ciliary muscle contraction on accommodation of the lens explored with a 3D model. Knaus KR, Hipsley A, Blemker SS. Biomech Model Mechanobiol. 2021 Jan 25. doi: 10.1007/s10237-021-01417-9.  
    3D Models Reveal the Influence of Achilles Subtendon Twist on Strain and Energy Storage. Knaus KR, Blemker SS. Front Bioeng Biotechnol. 2021 Feb 5;9:539135.
    Achilles Tendon Morphology Is Related to Triceps Surae Muscle Size and Peak Plantarflexion Torques During Walking in Young but Not Older Adults. Knaus KR, Ebrahimi A, Martin JA, Loegering IF, Thelen DG, Blemker SS. Front Sports Act Living. 2020 Aug 6;2:88.

Congratulations, Dr. Knaus

A special mesage to Katie Knaus from thesis advisor Dr. Silvia Blemker.

Nathanael Sallada, PhD

  • Characterization, Production, and Applications of Class II Hydrophobins in Drug Formulation and Delivery

    Characterization, Production, and Applications of Class II Hydrophobins in Drug Formulation and Delivery


    Hydrophobins: multifunctional biosurfactants for interface engineering. Berger BW, Sallada ND. J Biol Eng. 2019 Jan 23;13:10.
    Effect of gene copy number and chaperone coexpression on recombinant hydrophobin HFBI biosurfactant production in Pichia pastoris. Sallada ND, Harkins LE, Berger BW. Biotechnol Bioeng. 2019 Aug;116(8):2029-2040.
    A Structural and Functional Role for Disulfide Bonds in a Class II Hydrophobin. Sallada ND, Dunn KJ, Berger BW. Biochemistry. 2018 Feb 6;57(5):645-653. doi: 10.1021/acs.biochem.7b01166. Epub 2018 Jan 9.

Congratulations, Dr. Sallada

A special message for Nathanael Sallada from the Berger Lab.

Natasha Sheybani, PhD

  • Leveraging Focused Ultrasound to Potentiate Immunotherapy for Primary and Disseminated Solid Cancers

    Leveraging Focused Ultrasound to Potentiate Immunotherapy for Primary and Disseminated Solid Cancers


    Focused Ultrasound Hyperthermia Augments Release of Glioma-derived Extracellular Vesicles with Differential Immunomodulatory Capacity. Sheybani ND, Batts AJ, Mathew AS, Thim EA, Price RJ. Theranostics. 2020 Jun 12;10(16):7436-7447.
    Combination of thermally ablative focused ultrasound with gemcitabine controls breast cancer via adaptive immunity. Sheybani ND, Witter AR, Thim EA, Yagita H, Bullock TNJ, Price RJ. J Immunother Cancer. 2020 Aug;8(2):e001008. 

Congratulations, Dr. Sheybani

A special message for Natasha Sheybani from thesis Advisor Dr. Rich Price.

Shambhavi Singh, PhD

  • In Situ Gene Expression Profiling of Heterogeneous Cancer Cell States in Breast and Lung Carcinomas

    In Situ Gene Expression Profiling of Heterogeneous Cancer Cell States in Breast and Lung Carcinomas


    In situ 10-cell RNA sequencing in tissue and tumor biopsy samples. Singh S, Wang L, Schaff DL, Sutcliffe MD, Koeppel AF, Kim J, Onengut-Gumuscu S, Park KS, Zong H, Janes KA. Sci Rep. 2019 Mar 20;9(1):4836. doi: 10.1038/s41598-019-41235-9.
    Pan-cancer Drivers are Recurrent Transcriptional Regulatory Heterogeneities in Early-stage Luminal Breast Cancer. Singh S, Sutcliffe MD, Repich K, Atkins KA, Harvey JA, Janes KA. Cancer Res. 2021 Feb 2:canres.1034.2020.
    Fragmentation of Small-cell Lung Cancer Regulatory States in Heterotypic Microenvironments. Schaff DL*, Singh S*, Kim KB, Sutcliffe MD, Park KS, Janes KA. Cancer Res. 2021 Feb 2:canres.1036.2020.

Congratulations, Dr. Singh

A special message for Sham Singh from thesis Advisor Dr. Kevin Janes.

Naidi Sun, PhD

  • Photoacoustic Microscopy of Hemodynamics and Oxygen Metabolism at the Microscopic Level

    Photoacoustic Microscopy of Hemodynamics and Oxygen Metabolism at the Microscopic Level


    In vivo imaging of hemodynamic redistribution and arteriogenesis across microvascular network. Sun N, Ning B, Bruce AC, Cao R, Seaman SA, Wang T, Fritsche-Danielson R, Carlsson LG, Peirce SM, Hu S. Microcirculation. 2020 Apr;27(3):e12598. 
    Modified VEGF-A mRNA induces sustained multifaceted microvascular response and accelerates diabetic wound healing. Sun N, Ning B, Hansson KM, Bruce AC, Seaman SA, Zhang C, Rikard M, DeRosa CA, Fraser CL, Wågberg M, Fritsche-Danielson R, Wikström J, Chien KR, Lundahl A, Hölttä M, Carlsson LG, Peirce SM, Hu S. Sci Rep. 2018 Nov 30;8(1):17509. 

Laura Woo, PhD

  • Systems Pharmacology Approach for Identifying Mechanisms Driving Cardiomyocyte Proliferation

    Systems Pharmacology Approach for Identifying Mechanisms Driving Cardiomyocyte Proliferation


    J Mol Cell Cardiol 2019 Feb;127:204-214. High-content phenotypic assay for proliferation of human iPSC-derived cardiomyocytes identifies L-type calcium channels as targets. Laura A Woo, Svyatoslav Tkachenko, Mei Ding, Alleyn T Plowright, Ola Engkvist, Henrik Andersson, Lauren Drowley, Ian Barrett, Mike Firth, Peter Akerblad, Matthew J Wolf, Stefan Bekiranov, David L Brautigan, Qing-Dong Wang, Jeffrey J Saucerman.

Congratulations, Dr. Woo

A special message for Laura Woo from thesis Advisor Dr. Jeff Saucerman.

Jeffrey Xing, PhD

  • Genomic and Single-Cell Characterization of Clonal Proliferative Disorders of Large Granular Lymphocytes

    Genomic and Single-Cell Characterization of Clonal Proliferative Disorders of Large Granular Lymphocytes


    Frequent Somatic TET2 Mutations in Chronic NK-LGL Leukemia with Distinct Patterns of Cytopenias. Olson TL, Cheon H, Xing JC, Olson KC, Paila U, Hamele CE, Neelamraju Y, Shemo BC, Schmachtenberg MW, Sundararaman SK, Toro MF, Keller CA, Farber EA, Onengut-Gumuscu S, Garrett-Bakelman FE, Hardison RC, Feith D, Aakrosh R, Loughran T. Blood. 2021 Mar 30:blood.2020005831.

Ruixi Zhou, PhD

  • Self-Gated Cardiac MRI for Free-Breathing Simultaneous Cine, T1 Map and LGE Acquisition

    Self-Gated Cardiac MRI for Free-Breathing Simultaneous Cine, T1 Map and LGE Acquisition


    Free-breathing cine imaging with motion-corrected reconstruction at 3T using SPiral Acquisition with Respiratory correction and Cardiac Self-gating (SPARCS). Zhou R, Yang Y, ... Salerno M. Magn Reson Med. 2019 Aug;82(2):706-720.
    Simple motion correction strategy reduces respiratory-induced motion artifacts for k-t accelerated and compressed-sensing cardiovascular magnetic resonance perfusion imaging. Zhou R, Huang W, Yang Y, Chen X, Weller DS, Kramer CM, Kozerke S, Salerno M. J Cardiovasc Magn Reson. 2018 Mar 26;20(1):23.
    Dual-excitation flip-angle simultaneous cine and T1 mapping using spiral acquisition with respiratory and cardiac self-gating. Zhou R, Weller DS, Yang Y, Wang J, Jeelani H, Mugler JP 3rd, Salerno M. Magn Reson Med. 2021 Jul;86(1):82-96.

Congratulations, Dr. Zhou

A special message for Ruixi Zhou from thesis Advisor Dr. Michael Salerno.

Master of Science Students

Congratulations, Arlynn Baker

M.S. Thesis "Improved Methods for Agent-Based Modeling of Infarct Healing" defended October 20, 2020

Congratulations, Katya Gilbo, M.S.

M.S. Thesis "Development of T1-thermometry for Monitoring the Skull during MRgFUS using a 3D Spiral Ultra-Short Echo Time Sequence"...

Congratulations, Samarth Singh, M.S.

M.S. Thesis "Automated Volumetric Skull Segmentation Utilizing Ultra Short Echo Time Magnetic Resonance Imaging for MRgFUS" defended August...

Awards and Accolades of our Graduate Students

 

National Science Foundation Graduate Research Fellowship Program Bonnie Dougherty, Laura Dunphy, Natasha Sheybani

NIH NRSA F30 Jeff Xing, Bryan Chun

NIH K99/K00 Pathway to Independence Award Natasha Sheybani

NIH Training Grant or NIH Medical Scientist Training Program Jeffrey Xing, Bonnie Dougherty, Laura Woo, Sham Singh, Bryan Chun

UVA Engineering Distinguished Fellowship Yekaterina Gilbo

UVA Engineering Teaching Fellowship Katie Knaus, Natasha Sheybani

BME Going Pro Internship Bonnie Dougherty, Laura Woo

All-University Graduate Teaching Award Laura Dunphy

Sture G. Olsson Graduate Fellowship (School of Medicine) Bonnie Dougherty

Wagner Fellowship (School of Medicine) Laura Dunphy, Natasha Sheybani, Shambhavi Singh

American Society of Biomechanics Journal of Biomechanics Award Oral Presentation Katie Knaus

American Society of Biomechanics PhD Competition Katie Knaus

Controlled Release Society Student Poster Competition Natasha Sheybani

Interational FUS Symposium Travel Award Natasha Sheybani

ITSU International Society for Therapeutic Ultrasound Best Platform Talk Award Natasha Sheybani

MITRE’s Hack2Reacht First Place Jeffrey Xing

World Congress Biomechanics Diversity Travel Award Laura Caggiano

UVA Huskey Research Exhibition 1st Place Poster Laura Woo

PhD Graduates In The News