MR5, rm. 1111
​MR5, rm. 1213
Box 800759, Health System
Charlottesville, VA 22908
Google Scholar ResearchGate Griffin Lab


Donald Griffin improves clinical translation of acellular and cellular therapies through enhanced hydrogel-tissue integration, specifically focusing on the development of passive and active instructional microenvironments using microscale building blocks. He is an Associate Professor in the Department of Biomedical Engineering at the University of Virginia. After his training in Biomedical Engineering at the University of California, Los Angeles, Don joined the faculty at the University of Virginia in 2017.

His lab works on creating advanced biomaterials to support both fundamental science and translational approaches to tissue regeneration. They engineer biomaterials using a unique combination of microscale geometric control and novel chemistries. Don's work also bridges the academic-industry relationship with recognition as an inventor on several pending patents. Additionally, Don is a co-founder of a growing biomaterials company, Tempo Therapeutics (located in San Diego).


Post-Doc ​Chemical Engineering, UC Los Angeles, 2012-2016

Ph.D. ​Biomedical Engineering, UC Los Angeles, 2011

B.S. ​Biomedical Engineering, UC Davis, 2006

My research focuses on inventing micro-scale, instructive biomaterials for accelerated and improved recovery from injury and illness with a heavy emphasis on clinical translation.

Donald Richieri Griffin

Research Interests

Novel Biomaterial Development
Drug and Cell Delivery
Regenerative Medicine

Selected Publications

"Particle Hydrogels Based on Hyaluronic Acid Building Blocks." ACS Biomater. Sci. Eng., 2016, 2 (11), pp 2034–2041. E. Sideris, D.R. Griffin, Y. Ding, S. Li, W.M. Weaver, D. Di Carlo, T. Hsiai, T. Segura
"Accelerated wound healing by injectable microporous gel scaffolds assembled from annealed building blocks." Nature Materials, 2015, 14: 737–744. D.R. Griffin, W.M. Weaver, P. Scumpia, D. Di Carlo, T. Segura
"Hybrid Photopatterned Enzymatic Reaction (HyPER) for In situ Cell Manipulation." ChemBioChem, 2014, 15 (2): 233–242. D.R. Griffin, J. Borrajo, A. Soon, G.F. Acosta-Vélez, V. Oshita, N. Darling, J. Mack, T. Barker, M.L. Iruela-Arispe, T. Segura
"Synthesis of Photodegradable Macromers for Conjugation and Release of Bioactive Molecules." Biomacromolecules, 2013, 14 (4): 1199–1207. D.R. Griffin, J.L. Schlosser, S.F. Lam, T.H. Nguyen, H.D. Maynard, A.M. Kasko
"Photoselective Delivery of Model Therapeutics from Hydrogels." ACS Macro Letters, 2012, 1 (11): 1330–1334. D.R. Griffin, A.M. Kasko
"Photodegradable Macromers and Hydrogels for Live Cell Encapsulation and Release." Journal of the American Chemical Society, 2012, 134 (31): 13103–13107. D.R. Griffin, A.M. Kasko