Box 800759 Health System Charlottesville, Virginia 22908
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Kevin Janes is the John Marshall Money Professor of Biomedical Engineering and a Professor of Biochemistry & Molecular Genetics at the University of Virginia.  He received his B.S. and B.A. degrees in Biomedical Engineering and Spanish at Johns Hopkins University.  He was a Fulbright Scholar at La Universidad de Santiago de Compostela in Spain before attaining his Ph.D. in Bioengineering at M.I.T.  Dr. Janes completed a postdoctoral fellowship at Harvard Medical School in the Department of Cell Biology and began his faculty position at the University of Virginia in 2008.

At the University of Virginia, Dr. Janes was recognized as a Pew Scholar, a Packard Fellow, a Kavli Fellow, and a recipient of the NIH Director’s New Innovator Award.  He has chaired the Tumor Biochemistry and Endocrinology study section at the American Cancer Society and served on various study sections at the National Cancer Institute.  He is a member of the Board of Reviewing Editors for Science Signaling and a member of the Editorial Board for Cell Systems.  He co-leads an NIH-sponsored training grants in Systems & Biomolecular Data Science and a U54 Research Center in Cancer Systems Biology.  He was elected as a Fellow of the American Institute of Medical and Biological Engineering in 2020.


B.S. ​Johns Hopkins University, 1999

Ph.D. Massachusetts Institute of Technology, 2005​

Post-Doc ​Harvard Medical School, 2005-2008

"My research combines engineering principles with molecular biology to tackle fundamental problems in cancer and infectious disease."

Kevin Janes John Marshall Money Professor

Research Interests

Biomedical Data Sciences
Computational Systems Biology
Quantitative Biosciences

Selected Publications

Nucleocytoplasmic transport of active HER2 causes fractional escape from the DCIS-like state. Nat Commun, 14, 2110. WANG L*, PAUDEL BB*, MCKNIGHT RA, JANES KA. (2023)
Modeling the complete kinetics of coxsackievirus B3 reveals human determinants of host-cell feedback. Cell Syst, 12, 304-23.e1-e13.
Pan-cancer drivers are recurrent transcriptional regulatory heterogeneities in early-stage luminal breast cancer. Cancer Res, 81, 1840-52. SINGH S, SUTCLIFFE MD, REPICH K, ATKINS KA, HARVEY JA, JANES KA. (2021)
Fragmentation of small-cell lung cancer regulatory states in heterotypic microenvironments. Cancer Res, 81, 1853-67. SCHAFF DL*, SINGH S*, KIM K-B, SUTCLIFFE MD, PARK K-S, JANES KA. (2021)
Premalignant oligodendrocyte precursor cells stall in a heterogeneous state of replication stress prior to gliomagenesis. Cancer Res, 81, 1868-82. SUTCLIFFE MD, GALVAO RP, WANG L, KIM J, SINGH S, ZONG H†, JANES KA†. (2021)

Courses Taught

BME 4370/7370 Quantitative Biological Reasoning


Elected to the College of Fellows of the American Institute for Medical and Biological Engineering 2020