B. Bishal Paudel, Ph.D.

About

Dr. B. Bishal Paudel a systems biologist working at the interface of cancer biology and computational biology with research focused on understanding how dysfunctional biochemical signaling arise, how dysregulated signaling leads to emergent cancer phenotypes, and how those states can be engineered for desired outcomes.

Dr. Paudel's research uses a systems bioengineering approach to investigate how aberrant signaling leads to distinct metabolic and epigenetic states, and to devise strategies for therapeutic reprogramming. P3SystemsBiology lab is interested in two main research areas: (1) network-level regulation of metabolic heterogeneity and (2) oncogene-induced alterations in the epigenome and cancer phenotypes. He integrates bioengineering, mechanistic and statistical modeling with single-cell and population-level experiments to identify metabolic vulnerabilities and drivers of early cancer progression. 

Education

PhD, Chemical and Physical Biology, Vanderbilt University, 2018

BS, Chemistry, Maths-Physics, The College of Idaho, 2011