Hossack lab has a new Coulter Partnership Award of $136,00 for the design of a therapeutic ultrasound approach for the treatment of degenerative heart valve disease. The Principal Investigators are: John A. Hossack, Biomedical Engineering and Patricia Rodriguez Lozano, M.D., Cardiovascular Medicine. Clinical Co-Investigators include: Austin Robinson, M.D., Mohamed Morsy, M.D., and Christopher Kramer M.D., Cardiovascular Medicine and Radiology. New designs will be developed using Finite Element Analysis to evaluate technical tradeoffs. The project will involve simulation and in vitro testing. Some ex vivo testing will be performed subject to availability of suitable tissue.