Bijoy Kumar Kundu

Associate Professor of Radiology and Medical Imaging Associate Professor of Biomedical Engineering

Contact

bkk5a@virginia.edu

Mobile

(434) 924-0284

Location

480 Ray C. Hunt Dr., Room 183

Lab

480 Ray C. Hunt Dr.

Google Scholar Kundu Lab Preventing irreversible heart damage $1.9 Million Award Sugar and the Heart Blood Sugar and Hearts Failure

About

Bijoy K. Kundu, PhD, is an Associate Professor in the tenure track in the department of Radiology and Medical Imaging at the University of Virginia, Charlottesville. After completing his PhD in Nuclear Physics from the Bhabha Atomic Research Center, India, he pursued his post-doctoral work at the Indian Institute of Technology, Kanpur, India. He then moved to the Department of Radiology, University of Virginia, as a post-doctoral associate and moved up the faculty ranks. Dr. Kundu is a member of many scientific societies and reviewer of a number of peer-reviewed journals. The goals of his lab are to develop and optimize quantitative cardiac PET imaging techniques to address the hypothesis of metabolic remodeling in small animal modelsof myocardial injury and type 2 diabetes. His lab is currently funded by a grant from the National Institutes of Health.

Education

B.S. Physics, Bombay University, 1990

M.S. Physics, Bombay University, 1992

Ph.D. Physics, Bhabha Atomic Research Center, 1998

To develop quantitative cardiac PET imaging techniques to address metabolic remodeling in small animal models of myocardial injury & type 2 diabetes.

Bijoy Kumar Kundu Associate Professor of Biomedical Engineering

Research Interests

Medical and Molecular Imaging

Cardiovascular Engineering

Selected Publications

Noninvasive Detection of Early Metabolic Left Ventricular Remodeling in Systemic Hypertension. Cardiology 2016; 133(3):157-162. *corresponding author. PMC4677787 Hamirani Y, Kundu Bk*, Zhong M,...,taegtmeyer H, Bourque J.

ABS

Determination of Fatty Acid Metabolism with Dynamic [11C]Palmitate Positron Emission Tomography of Mouse Heart In Vivo. Mol Imaging. 2015 Sep 1;14:516-25. PMID 26462138. *corresponding author. PMC4625801 Li Y, Huang T, Zhang X, Zhong M, He J, Keller S, Berr S, Kundu Bk*

ABS

PET imaging detection of macrophages with a formyl peptide receptor antagonist. Nucl Med Biol. 2015 Apr;42(4):381-6. PMC4405787 Zhang Y, Kundu Bk, Zhong M, Huang T, Li J, Chordia Md, Chen Mh, Pan D, He J, Shi W

ABS

Remodeling of glucose metabolism precedes pressure overload-induced left ventricular hypertrophy: review of a hypothesis. Cardiology. 2015;130(4):211-20. PMC4394867. Kundu Bk, Zhong M, Sen S, Davogustto G, Keller Sr, Taegtmeyer H*,*corresponding Author

ABS

Myocardial Metabolic Remodeling in Hypertension Induced Left Ventricular Hypertrophy, Abstract, J Am Coll Cardiol 2014 April; 62(12):A1011. Hamirani, Y, Zhong M, Mcbride a, Bourque J, Kundu Bk*, *corresponding Author

Glucose regulation of load-induced mTOR signaling and ER stress in mammalian heart. J Am Heart Assoc. 2013 May 17;2(3):e004796. PMC3698799. Sen S, Kundu Bk*, Wu Hc*, Hashmi Ss, Guthrie P, Locke Lw, Matherne Gp, Berr Ss, Terwelp M, Scott B, Carranza S, Frazier H, Glover Dk, Dillman Wh, Gambello Mj, Entman Ml,taegtmeyer H

ABS

Quantitative PET imaging detects early metabolic remodeling in a mouse model of pressure-overload left ventricular hypertrophy in vivo. J Nucl Med 2013 April;54(4):609-15. PMC3727159. Zhong M, Alonso Ce, Taegtmeyer H, Kundu Bk.

ABS

Optimization of a Model Corrected Blood Input Function from Dynamic FDG-PET Images of Small Animal Heart In Vivo. IEEE Trans Nucl Sci. 2013 October; 60(5):3417-3422. PMC3985393. Zhong M, Kundu Bk

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FDG-PET Quantification of Lung Inflammation with Image-Derived Blood Input Function in Mice. Int J Mol Imag, Volume 2011, Article ID 356730, Epub 2011, Dec 10, 2011. PMC3236466. Locke Lw, Williams Mb, Fairchild Kd, Zhong M, Kundu Bk, Berr Ss.

Image-derived input function from cardiac gated maximum a posteriori reconstructed PET images in mice. Mol Imag Biol. 2011 Apr;13(2):342-347. PMC303677 Locke Lw, Berr Ss, Kundu Bk

ABS

Featured Grants & Projects

Kundu Lab Projects Development of improved methods for quantification of metabolism and blood flow from dynamic PET images of rodent and human heart in vivo. Determine the time course of metabolic alterations in the SHR hearts and relate them to the development of LVH and HF using dynamic PET imaging and kinetic modeling in conjunction with MRI and molecular and metabolic analyses. Development of novel methods for improved demonstration of function brain abnormalities from dynamic FDG PET images of human brain using kinetic modeling. Development of algorithms for automatic segmentation of breast lesions based on ANN from dynamic images obtained using a dedicated breast PET scanner.