Clint Miller

Bio

"We leverage natural genetic variation and data-driven approaches to identify new risk factors and treatments for cardiovascular disease."

Clint Miller

Clint Miller studies the genetic and environmental risk factors for coronary artery disease and other complex cardiovascular diseases using a combination of large-scale multi-omics profiling and genetic and drug perturbations. He is an Assistant Professor in Public Health Sciences and a resident member of the Center for Public Health Genomics. He is also a member of the Data Science Institute, Robert Berne Cardiovascular Institute, and holds secondary appointments in Biomedical Engineering and Biochemistry and Molecular Genetics. He joined UVA in 2017.

Clint was previously an Instructor at Stanford University in Cardiovascular Medicine from 2015-2017. He earned his PhD in Pharmacology at the University of Rochester with Chen Yan investigating cyclic nucleotide signaling pathways in the heart and completed his postdoctoral fellowship in human genetics and genomics at Stanford University with Tom Quertermous. There he investigated the regulatory mechanisms of coronary artery disease loci identified from genome-wide association studies. The Miller Lab studies the genetic and environmental risk factors for coronary artery disease and other complex cardiovascular diseases using a combination of large-scale multi-omics profiling and genetic and drug perturbations. They integrate computational and functional genomic analyses, vascular biology and systems pharmacology approaches to study causal regulatory networks driving the disease process. Their goal is to identify novel markers to better classify patients with cardiovascular disease as well as inform tailored treatments that target dysregulated pathways in the vessel wall.