Wilsdorf A005, A007 385 McCormick Road
Wilsdorf A005, A007
The Lampe Biomaterials Group Center for Brain Immunology and Glia (BIG) Center for Advanced Biomanufacturing (CAd-Bio) Google Scholar Research Gate


Kyle Lampe is an Associate Professor in the Department of Chemical Engineering at the University of Virginia, and by courtesy, Biomedical Engineering and Neuroscience. He was previously a Ruth L. Kirschstein NIH NRSA postdoctoral scholar at Stanford University in the department of Materials Science and Engineering. Kyle completed his Ph.D. and B.S. in Chemical Engineering from the University of Colorado, Boulder and the Missouri University of Science and Technology (Rolla, MO), respectively. Currently funded by NIH, NSF, and the Commonwealth Health Research Board, the Lampe Group investigates biomaterials for tissue engineering, regenerative medicine, and drug delivery within the central nervous system. We develop materials including synthetic polymers, recombinant engineered proteins, and self-assembling peptides and enjoy collaborating widely throughout engineering, biology, and medicine.


B.S. ​Missouri University of Science and Technology, 2004

Ph.D. University of Colorado, Boulder, 2009

Post-Doc ​Stanford University, Materials Science and Engineering, 2010-2013

"We hope to better understand and treat diseases and injuries of the brain."

Research Interests

Tissue Engineering and Regenerative Medicine
Materials and Advanced Manufacturing for Biological Applications
Drug Delivery
Biotechnology and Biomolecular Engineering

Selected Publications

"The Need for Tissue Engineered Models to Facilitate the Study of Oligodendrocyte Progenitor Cells in Traumatic Brain Injury and Repair," Current Opinion in Biomedical Engineering, 22: 100378 (2022) RA MAZUR, R YOKOSAWA, PJ VANDEVORD, KJ LAMPE
"Guiding Oligodendrocyte Precursor Cell Maturation with Urokinase Plasminogen Activator-degradable Elastin-like Protein Hydrogels," Biomacromolecules, 21: 4724-4736 (2020) E MECO, WS ZHENG, A SHARMA, KJ LAMPE
"A stimuli-responsive, pentapeptide, nanofiber hydrogel for tissue engineering," Journal of the American Chemical Society, (2019) JD TANG, C MURA, KJ LAMPE
"Oligodendrocyte Precursor Cell Viability, Proliferation, and Morphology is Dependent on Mesh Size and Storage Modulus in 3D Poly(ethylene glycol) Based Hydrogels," ACS Biomater. Sci. Eng. (2017) LN RUSSELL, KJ LAMPE
"Maintenance of neural progenitor cell stemness in 3D hydrogels requires matrix remodelling," Nature Materials 16, 1233-1242 (2017) CM MADL, BL LESAVAGE, RE DEWI, CB DINH, RS STOWERS, M KHARITON, KJ LAMPE, DNGUYEN, O CHAUDHURI, A ENEJDER & SC HEILSHORN,

Courses Taught

CHE 4449/6449 - Polymer Science and Engineering EACH FALL
APMA 3110 - Applied Statistics and Probability SPRING 2022
CHE 6561 - Advanced Biomaterials and Tissue Engineering SPRING 2023


Distinguished Young Alumni Award, Miner Alumni Association (Missouri University of Science and Technology) 2020
NIH NIBIB "Trailblazer" grant 2019
American Society of Engineering Education (ASEE) "20 under 40" faculty 2018
Translational Health Research Insitute of Virginia (THRIV) Mentored Career Development Award 2017

Featured Grants & Projects

Engineering the design of self-assembling, shear thinning pentapeptide hydrogels to promote neural cell growth and differentiation National Science Foundation
Self-assembling, shear-thinning peptide hydrogels to support cell transplantation and host cell interaction after ischemic stroke Commonwealth Health Research Board
A novel drug loading method to protect neural cells from oxidative stress induced by a hypoxic/ischemic inflammatory environment National Institutes of Health
Engineering a Neural Tissue Model of Oligodendroglial and Matrix Remodeling after Biophysical Injury National Science Foundation
National Science Foundation