Bio

B.S. ​Missouri University of Science and Technology, 2004​Ph.D. University of Colorado, Boulder, 2009Post-Doc ​Stanford University, Materials Science and Engineering, 2010-2013

"We hope to better understand and treat diseases and injuries of the brain."

Kyle J. Lampe, Associate Professor

Kyle is an Associate Professor in the Department of Chemical Engineering at the University of Virginia, and by courtesy, Biomedical Engineering and Neuroscience. He was previously a Ruth L. Kirschstein NIH NRSA postdoctoral scholar at Stanford University with Prof. Sarah Heilshorn in the department of Materials Science and Engineering. Kyle completed his Ph.D. and B.S. in Chemical Engineering from the University of Colorado, Boulder and the Missouri University of Science and Technology (Rolla, MO), respectively. The Lampe Group investigates biomaterials for tissue engineering, regenerative medicine, and drug delivery within the central nervous system, developing materials including synthetic polymers, recombinant engineered proteins, and self-assembling peptides.

Awards

  • Distinguished Young Alumni Award, Miner Alumni Association (Missouri University of Science and Technology) 2020
  • NIH NIBIB "Trailblazer" grant 2019
  • American Society of Engineering Education (ASEE) "20 under 40" faculty 2018
  • Translational Health Research Insitute of Virginia (THRIV) Mentored Career Development Award 2017
  • Postdoctoral Research Award – Stanford University Postdoctoral Association, Stanford University, School of Engineering recipient 2012
  • Ruth L. Kirschstein NIH NRSA Postdoctoral Fellowship 2011-2013

Research Interests

  • Biomaterials
  • Tissue Engineering and Regenerative Medicine
  • Materials and Advanced Manufacturing for Biological Applications
  • Drug Delivery
  • Biotechnology and Biomolecular Engineering

Selected Publications

  • "The Need for Tissue Engineered Models to Facilitate the Study of Oligodendrocyte Progenitor Cells in Traumatic Brain Injury and Repair," Current Opinion in Biomedical Engineering, 22: 100378 (2022) ABS RA Mazur, R Yokosawa, PJ VandeVord, KJ Lampe
  • "Guiding Oligodendrocyte Precursor Cell Maturation with Urokinase Plasminogen Activator-degradable Elastin-like Protein Hydrogels," Biomacromolecules, 21: 4724-4736 (2020) ABS E Meco, WS Zheng, A Sharma, KJ Lampe
  • "A stimuli-responsive, pentapeptide, nanofiber hydrogel for tissue engineering," Journal of the American Chemical Society, (2019) ABS JD Tang, C Mura, KJ Lampe
  • "Oligodendrocyte Precursor Cell Viability, Proliferation, and Morphology is Dependent on Mesh Size and Storage Modulus in 3D Poly(ethylene glycol) Based Hydrogels," ACS Biomater. Sci. Eng. (2017) ABS LN Russell, KJ Lampe
  • "Maintenance of neural progenitor cell stemness in 3D hydrogels requires matrix remodelling," Nature Materials 16, 1233-1242 (2017) ABS CM Madl, BL LeSavage, RE Dewi, CB Dinh, RS Stowers, M Khariton, KJ Lampe, DNguyen, O Chaudhuri, A Enejder & SC Heilshorn,
  • "Design of 3D engineered protein hydrogels for tailored control of neurite growth," Acta Biomaterialia, 9: 5590-5599 (2013) ABS KJ Lampe, AL Antaris, SC Heilshorn
Google Scholar
ResearchGate

Courses Taught

  • CHE 4449/6449 - Polymer Science and Engineering Fall Semester
  • CHE 3347/6447 - Biochemical Engineering Spring Semester
  • APMA 3110 - Applied Statistics and Probability

Featured Grants & Projects

  • Engineering the design of self-assembling, shear thinning pentapeptide hydrogels to promote neural cell growth and differentiation

    National Science Foundation

  • Self-assembling, shear-thinning peptide hydrogels to support cell transplantation and host cell interaction after ischemic stroke

    Commonwealth Health Research Board

  • A novel drug loading method to protect neural cells from oxidative stress induced by a hypoxic/ischemic inflammatory environment

    National Institutes of Health

  • Engineering a Neural Tissue Model of Oligodendroglial and Matrix Remodeling after Biophysical Injury

    National Science Foundation