Bio

B.S. ​Missouri University of Science and Technology, 2004​Ph.D. University of Colorado, Boulder, 2009Post-Doc ​Stanford University, Materials Science and Engineering, 2010-2013

"We hope to better understand and treat diseases and injuries of the central nervous system, that is, the brain and spinal cord."

Kyle J. Lampe, Assistant Professor

Kyle is an Assistant Professor in the Department of Chemical Engineering at the University of Virginia, and by courtesy, Biomedical Engineering and Neuroscience. He was previously a Ruth L. Kirschstein NIH NRSA postdoctoral scholar at Stanford University with Prof. Sarah Heilshorn in the department of Materials Science and Engineering. Kyle completed his Ph.D. and B.S. in Chemical Engineering from the University of Colorado, Boulder and the Missouri University of Science and Technology (Rolla, MO), respectively. The Lampe Group investigates biomaterials for tissue engineering, regenerative medicine, and drug delivery within the central nervous system, developing materials including synthetic polymers, recombinant engineered proteins, and self-assembling peptides.

Awards

  • Translational Health Research Insitute of Virginia (THRIV) Mentored Career Development Award 2017
  • Postdoctoral Research Award – Stanford University Postdoctoral Association, Stanford University, School of Engineering recipient 2012
  • Ruth L. Kirschstein NIH NRSA Postdoctoral Fellowship 2011-2013
  • U.S. Dept. of Education – Graduate Assistantship in Areas of National Need (GAANN) 2005-2008

Research Interests

  • Biomaterials
  • Tissue Engineering and Regenerative Medicine
  • Materials and Advanced Manufacturing for Biological Applications
  • Drug Delivery
  • Biotechnology and Biomolecular Engineering (Biomolecular Design, Cellular and Molecular Bioengineering)
  • Bio-inspired systems

Selected Publications

  • "A stimuli-responsive, pentapeptide, nanofiber hydrogel for tissue engineering," Journal of the American Chemical Society, (2019) ABS JD Tang, C Mura, KJ Lampe
  • "Oligodendrocyte Precursor Cell Viability, Proliferation, and Morphology is Dependent on Mesh Size and Storage Modulus in 3D Poly(ethylene glycol) Based Hydrogels," ACS Biomater. Sci. Eng. (2017) ABS LN Russell, KJ Lampe
  • "Maintenance of neural progenitor cell stemness in 3D hydrogels requires matrix remodelling," Nature Materials 16, 1233-1242 (2017) ABS CM Madl, BL LeSavage, RE Dewi, CB Dinh, RS Stowers, M Khariton, KJ Lampe, DNguyen, O Chaudhuri, A Enejder & SC Heilshorn,
  • "Design of 3D engineered protein hydrogels for tailored control of neurite growth," Acta Biomaterialia, 9: 5590-5599 (2013) ABS KJ Lampe, AL Antaris, SC Heilshorn
  • "Improving viability of stem cells during syringe needle flow through the design of hydrogel cell carriers," Tissue Engineering Part A, 18: 806-815 (2012) ABS BA Aguado, W Mulyasasmita, J Su, KJ Lampe, SC Heilshorn
  • "The administration of BDNF and GDNF to the brain via PLGA microparticles patterned within a degradable PEG-based hydrogel: protein distribution and the glial response," Journal of Biomedical Materials Research Part A, 96A: 595-607 (2011) ABS KJ Lampe, DS Kern, MJ Mahoney, KB Bjugstad
Google Scholar
ResearchGate

Courses Taught

  • CHE 4449/6449 - Polymer Science and Engineering Fall Semester
  • CHE 3347/6447 - Biochemical Engineering Spring Semester

Featured Grants & Projects

  • Neural repair via self-assembling biomaterial hydrogels designed by molecular dynamic simulations

    The Thomas F. and Kate Miller Jeffress Memorial Trust and the Hazel Thorpe Carman and George Gay Carman Trust.

  • Bioengineered Hydrogels to Facilitate 3D Neural Stem Cell Survival and Growth in a Stroke Environment

    Mentored Careerd Development Award

    Translational Health Research Institute of Virginia (THRIV)