B.S. in Chemistry, Grinnell College, 1977Ph.D. in Physical Chemistry, Wake Forest University, 1986Postdoc, Chemistry , University of VirginiaPostdoc, Cardiology and Radiology, University of Virginia
"We have developed noninvasive methods for imaging blood perfusion, effective in imaging blood flow to the kidneys, lungs, heart, and brain in humans."
Stuart S. Berr, Professor of Biomedical Engineering
Our laboratory is involved with developing magnetic resonance (MR) techniques as a tool for basic biomedical research. We have developed noninvasive, non-contrast-enhanced methods for imaging blood perfusion, demonstrated to be effective in imaging blood flow to the kidneys, lungs, heart, and brain in humans. We were also the first to demonstrate the feasibility of imaging the lung using hydrogen-based MR methods.
We have also been developing micro-imaging techniques for the study of the heart and vascular system in mice and rats. This project has been particularly challenging due to the high spatial and temporal resolution requirements.
Medical and Molecular Imaging
PET imaging of tumor associated macrophages using mannose coated (64)Cu liposomes. Biomaterials. 2012 Jul 26. Locke LW, Mayo MW, Yoo AD, Williams MB, Berr SS.
Percutaneous intervention in peripheral artery disease improves calf muscle phosphocreatine recovery kinetics: a pilot study. Vasc Med. 2012 Feb;17(1):3-9. West AM, Anderson JD, Epstein FH, Meyer CH, Hagspiel KD, Berr SS, Harthun NL, Weltman AL, Annex BH, Kramer CM.
A nonpeptide angiotensin II type 2 receptor agonist does not attenuate postmyocardial infarction left ventricular remodeling in mice. J Cardiovasc Pharmacol. 2012 Apr;59(4):363-8. Jehle AB, Xu Y, Dimaria JM, French BA, Epstein FH, Berr SS, Roy RJ, Kemp BA, Carey RM, Kramer CM.
Low-density lipoprotein lowering does not improve calf muscle perfusion, energetics, or exercise performance in peripheral arterial disease. 2011 Aug 30;58(10):1068-76. West AM, Anderson JD, Epstein FH, Meyer CH, Wang H, Hagspiel KD, Berr SS, Harthun NL, Weltman AL, Dimaria JM, Hunter JR, Christopher JM, Kramer CM. J Am Coll Cardiol.
FDG-PET Quantification of Lung Inflammation with Image-Derived Blood Input Function in Mice. Int J Mol Imaging. 2011; 2011: 356730. Epub 2011 Dec 10. Locke LW, Williams MB, Fairchild KD, Zhong M, Kundu BK, Berr SS.