Associate Professor of Bioengineering, Northeastern University
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UVA Biomedical Engineering Seminar Series
Unraveling Cellular State Transitions: Through the Lens of Computational Systems Biology
Presented by:
Mingyang Lu, PhD
Associate Professor of Bioengineering, Northeastern University
Date: Friday, September 26, 2025
Location: MR5, Room 1041
Time:
- 1:45 PM – Refreshments Served
- 2:00 PM – Presentation
- 3:00 PM – Meet the Speaker
Zoom Access:
- Zoom link
- Meeting ID: 924 6712 8585
- Passcode: 223686
Talk Overview
Understanding the role of gene regulation in driving cellular state transitions is a major challenge in biology, especially in contexts such as stem cell differentiation, cell reprogramming, and disease progression. Advances in transcriptomics sequencing have provided invaluable data, but a holistic view of gene and network collaboration remains elusive.
Dr. Lu will present computational systems biology methods that illuminate the interplay between gene regulatory networks, single-cell gene expression dynamics, and cellular state transitions. His integrative approach combines top-down bioinformatics with bottom-up quantitative systems biology techniques, offering new tools to explore the mechanisms of cell fate determination.
About the Speaker
Dr. Mingyang Lu earned his Ph.D. in Biochemistry and Molecular Biology from Baylor College of Medicine in 2010 and completed postdoctoral training at Rice University. He launched his computational systems biology lab at The Jackson Laboratory in 2016 and moved to Northeastern University’s Department of Bioengineering in 2020.
His research focuses on developing methodologies in computational systems biology to understand gene regulatory mechanisms in cellular processes using genomics data.
Questions?
Email: GinaT@virginia.edu
