The University of Virginia'sBiocomplexity Institute and Initiativeteam is on the front lines of the national modeling, monitoring, planning and response to COVID-19. The institute integrates scientific research – from genetic sequencing to policy analysis – to tackle the complex task of understanding massively interacting systems and predicting solutions to issues affecting human health, well-being and habitat. The methodology for the research lies in information biology, which is the synthesis of mathematics, computation, informatics, and biology. The Biocomplexity Institute team is led byChristopher L. Barrett, the institute's executive director, Distinguished Professor in Biocomplexity and faculty member inUVA Engineering's Department of Computer Science.Madhav Marathe, a Distinguished Professor in Biocomplexity and faculty member in the Department of Computer Science, is director of the institute's Network Systems Science and Advanced Computing Division.Anil Vullikanti, professor of computer science, andHenning S. Mortveit, associate professor in the Department of Engineering Systems and Environment, are also members of the institute's team.