High-Resolution Brain Connectivity Mapping

The imaging of water diffusion using MRI enables the imaging of axonal brain connectivity. CBIG's focus in this research is to understand the higher signal-to-noise ratio (SNR) offered by the ultra-high field (UHF) strengths to map brain connectivity at unprecedented spatial and angular resolutions. We utilize novel algorithms to minimize inter-shot motion induced distortions in multi-shot MRI; the multi-shot acquisition scheme provides improved SNR, which translates to higher spatial resolution. We also introduce novel compressed sensing strategies and joint K-Q undersampling strategies to further improve resolution.