Founding Dean of the School of Data Science and Professor of BME
Leading a range of initiatives to encourage and facilitate the use of big data in large-scale research across the scientific and technological disciplines. Special emphasis on structural bioinformatics and systems pharmacology.
Developing new systems biology approaches to understand fundamental mechanisms of immune regulation and dysregulation, with an ultimate objective of identifying strategies to design and improve immunotherapies.
At the interface of systems biology, quantitative pharmacology and cancer biology, we link genetic, epigenetic and signaling mechanisms through which cells (in healthy or cancer states) respond to perturbations such as cytokines, stress and cancer drugs.
Experimental and computational methods to study fundamental aspects of cell signaling regulation and applied aspects of cell signaling, including the efficacy of therapeutics that target particular signaling pathways in cancer.
Developing ultrasound-activated drug and gene delivery systems for treating cancer and Parkinson’s disease. Investigating the mechanisms through which collateral arteries grow and adapt in response to changes in blood flow.