Clinical Trial is First of Its Kind in the World, Combining Focused Ultrasound and Immunotherapy to Treat Breast Cancer in Humans

Tackling Cancer Through team Science.

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Price Lab

Focused Ultrasound Foundation

UVA BME Cancer Research
UVA Professor’s Promising Cancer Drug Attracts $25 Million in Funding

UVA biomedical engineering professor Kimberly Kelly founded ZielBio to bring new cancer treatments to market.

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Kelly Lab

Zielbio, Inc

Biomedical Engineering Research at UVA
A Quantitative Portrait of Cancer

Associate professor of chemical engineering Matthew Lazzara is attempting to unravel the cell signaling systems associated with two particularly deadly forms of cancer.

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Matt Lazzara

Coulter Translational Research Partnership

Cancer

Cancer is a multiscale disease of biomolecules, cells, and tissues—engineering approaches provide biomedical insights, diagnoses, and therapies that will ultimately benefit cancer patients.

BME Primary Faculty in this Area

Tom Barker, Ph.D.

Tom Barker, Ph.D.

Professor

Exploring and therapeutically exploiting the fundamental links between fibroblast adaptation to their mechanical microenvinronment and their myofibroblastic differentiation during tissue fibrosis.

The Matrix Biology and Engineering Lab
Bryan Berger, PhD

Bryan Berger, PhD

Associate Professor

We utilize synthetic biology to address emergent challenges across diverse areas such as advanced biomanufacturing, improving drug bioavailability and combating antimicrobial resistance.
Philip Bourne, Ph.D.

Philip Bourne, Ph.D.

Founding Dean of the School of Data Science and Professor of BME

Leading a range of initiatives to encourage and facilitate the use of big data in large-scale research across the scientific and technological disciplines. Special emphasis on structural bioinformatics and systems pharmacology.

Wikipedia Profile
Sepideh Dolatshahi, PhD

Sepideh Dolatshahi, PhD

Assistant Professor

Developing new systems biology approaches to understand fundamental mechanisms of immune regulation and dysregulation, with an ultimate objective of identifying strategies to design and improve immunotherapies.

Faculty Profile
Mohammad Fallahi-Sichani

Mohammad Fallahi-Sichani

Assistant Professor

At the interface of systems biology, quantitative pharmacology and cancer biology, we link genetic, epigenetic and signaling mechanisms through which cells (in healthy or cancer states) respond to perturbations such as cytokines, stress and cancer drugs.

Faculty Profile
Brent French, Ph.D.

Brent French, Ph.D.

Professor

Combining advanced methods of targeted drug and gene delivery with biomedical imaging in vivo to explore novel targets and treatment strategies in cardiovascular disease and cancer.

Faculty Profile
Kevin Janes, Ph.D.

Kevin Janes, Ph.D.

Associate Professor

Designing and using new experimental and computational approaches for analyzing cell signaling and transcriptional networks in cancer.

Cell-Signaling Bioanalysis Laboratory
Kim Kelly, Ph.D.

Kim Kelly, Ph.D.

Professor

Developing phage-based nanoparticle techniques for diagnostic imaging, drug target identification, and drug delivery in the setting of pancreatic cancer.

Faculty Profile
Matthew Lazzara, Ph.D.

Matthew Lazzara, Ph.D.

Associate Professor

Experimental and computational methods to study fundamental aspects of cell signaling regulation and applied aspects of cell signaling, including the efficacy of therapeutics that target particular signaling pathways in cancer.

Cell Signaling Engineering Lab
Kristen Naegle, Ph.D.

Kristen Naegle, Ph.D.

Associate Professor

Using data- and computational-driven approaches to predict, and experimental approaches to test, the regulation and function of tyrosine phosphorylation in complex networks.

Faculty Profile
Rich Price, Ph.D.

Rich Price, Ph.D.

Professor

Developing ultrasound-activated drug and gene delivery systems for treating cancer and Parkinson’s disease. Investigating the mechanisms through which collateral arteries grow and adapt in response to changes in blood flow.

Price Lab
Gustavo Rohde, Ph.D.

Gustavo Rohde, Ph.D.

Associate Professor

Developing computational predictive models using machine learning and signal and image processing with applications in pathology, radiology, systems biology and mobile sensing.

Faculty Profile

BME Joint Faculty in Cancer Applications

Mark Kester, PhD

Mark Kester, PhD

Professor of Pharmacology, NanoSTAR Director

Developing innovative nanotechnologies for targeted drug delivery in cancer and cardiovascular diseases; pioneered the use of sphingolipids as therapeutics.

Faculty Profile
Nathan Sheffield, PhD

Nathan Sheffield, PhD

Assistant Professor of Public Health Sciences

Using computation to ask and answer biological questions, specifically how DNA encodes regulatory networks that enable cellular differentiation?

Sheffield Lab
Mark Williams, PhD

Professor of Radiology and Medical Imaging

Novel medical imaging systems to be used for early detection and characterization of disease, and for guiding and assessing therapy.

Faculty Profile
Chongzhi Zang, PhD

Chongzhi Zang, PhD

Assistant Professor of Public Health Sciences

Algorithm development for high-throughput genomic data analytics and integrative modeling of gene regulatory networks in mammalian cell systems.

Faculty Profile

More about Cancer Research at UVA

UVA Cancer Center

UVA Cancer Center

A National Cancer Institute (NCI)-designated cancer center

Cancer cell signaling | Molecular genetics and epigenetics | Chemical and structural biology | Immunology and immunotherapy | Women’s oncology | Cancer control and population health.

Cancer Center Website

Kelly Lab UVA — Inquisitiveness, Passion, and Persistence

Pancreatic cancer researcher Lindsay Brinton (BS '09, PhD '16) reflects on what it takes to be a biomedical researcher.

November 18 PhD Qualifying Exam Presentation by Marzieh Lenjani
November 18 Doctoral Dissertation Proposal for Robert Costanzo
November 20 Future Leaders Speaker Series: Sponsored by McGuireWoods
See All Events

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Cancer

BME Primary Faculty in this Area

Professor

Bryan Berger, PhD

Associate Professor

Founding Dean of the School of Data Science and Professor of BME

Assistant Professor

Assistant Professor

Professor

Associate Professor

Professor

Associate Professor

Associate Professor

Professor

Associate Professor

BME Joint Faculty in Cancer Applications

Professor of Pharmacology, NanoSTAR Director

Assistant Professor of Public Health Sciences

Professor of Radiology and Medical Imaging

Assistant Professor of Public Health Sciences

More about Cancer Research at UVA

A National Cancer Institute (NCI)-designated cancer center

Inquisitiveness, Passion, and Persistence