New Faculty Member Has a Strategy for Unraveling the Complexity of Cancer Research

Mohammad Fallahi-Sichani moved his research lab to UVA, in part because this is a great place for a cancer systems biologist to take on a complex challenge.

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Mohammad Fallahi-Sichani, Biomedical Engineering

Laboratory of Systems Biology and Quantitative Pharmacology
A Research Hat Trick

When an athlete scores three times in a single game, it's called a hat trick. If scientific research had hat tricks, Janes would have fans screaming in the stands.

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Kevin Janes, UVA Biomedical Engineering

Janes Lab
Meet Sepideh Dolatshahi

In this video, Sepideh Dolatshahi, a new assistant professor of biomedical engineering, explains how, early in her Ph.D. training in electrical engineering, she became interested...

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Sepideh Dolatshahi, PhD

Biomedical Data Sciences and Systems Biology Research

Infectious Diseases Research in Biomedical Engineering

Cancer Research in Biomedical Engineering

Dolatshahi Lab

Cancer

Cancer is a multiscale disease of biomolecules, cells, and tissues—engineering approaches provide biomedical insights, diagnoses, and therapies that will ultimately benefit cancer patients.

BME Primary Faculty in this Area

Tom Barker, Ph.D.

Tom Barker, Ph.D.

Professor

Exploring and therapeutically exploiting the fundamental links between fibroblast adaptation to their mechanical microenvinronment and their myofibroblastic differentiation during tissue fibrosis.

The Matrix Biology and Engineering Lab
Bryan Berger, Ph.D.

Bryan Berger, Ph.D.

Associate Professor

We utilize synthetic biology to address emergent challenges across diverse areas such as advanced biomanufacturing, improving drug bioavailability and combating antimicrobial resistance.

Faculty Profile
Philip Bourne, Ph.D.

Philip Bourne, Ph.D.

Founding Dean of the School of Data Science and Professor of BME

Leading a range of initiatives to encourage and facilitate the use of big data in large-scale research across the scientific and technological disciplines. Special emphasis on structural bioinformatics and systems pharmacology.

Faculty Profile
Sepideh Dolatshahi, Ph.D.

Sepideh Dolatshahi, Ph.D.

Assistant Professor

Developing new systems biology approaches to understand fundamental mechanisms of immune regulation and dysregulation, with an ultimate objective of identifying strategies to design and improve immunotherapies.

Dolatshahi Lab
Mohammad Fallahi-Sichani, Ph.D.

Mohammad Fallahi-Sichani, Ph.D.

Assistant Professor

At the interface of systems biology, quantitative pharmacology and cancer biology, we link genetic, epigenetic and signaling mechanisms through which cells (in healthy or cancer states) respond to perturbations such as cytokines, stress and cancer drugs.

Systems Biology and Quantitative Pharmacology Lab
Brent French, Ph.D.

Brent French, Ph.D.

Professor

Combining advanced methods of targeted drug and gene delivery with biomedical imaging in vivo to explore novel targets and treatment strategies in cardiovascular disease and cancer.

Faculty Profile
Kevin Janes, Ph.D.

Kevin Janes, Ph.D.

Professor

Designing and using new experimental and computational approaches for analyzing cell signaling and transcriptional networks in cancer.

Janes Lab
Kim Kelly, Ph.D.

Kim Kelly, Ph.D.

Professor

Developing phage-based nanoparticle techniques for diagnostic imaging, drug target identification, and drug delivery in the setting of pancreatic cancer.

Kelly Lab
Matthew Lazzara, Ph.D.

Matthew Lazzara, Ph.D.

Associate Professor

Experimental and computational methods to study fundamental aspects of cell signaling regulation and applied aspects of cell signaling, including the efficacy of therapeutics that target particular signaling pathways in cancer.

Cell Signaling Engineering Lab
Kristen Naegle, Ph.D.

Kristen Naegle, Ph.D.

Associate Professor

Using data- and computational-driven approaches to predict, and experimental approaches to test, the regulation and function of tyrosine phosphorylation in complex networks.

Naegle Lab
Rich Price, Ph.D.

Rich Price, Ph.D.

Professor

Developing ultrasound-activated drug and gene delivery systems for treating cancer and Parkinson’s disease. Investigating the mechanisms through which collateral arteries grow and adapt in response to changes in blood flow.

Price Lab
Gustavo Rohde, Ph.D.

Gustavo Rohde, Ph.D.

Professor

Developing computational predictive models using machine learning and signal and image processing with applications in pathology, radiology, systems biology and mobile sensing.

Imaging and Data Science Lab
Natasha Sheybani, Ph.D.

Natasha Sheybani, Ph.D.

Assistant Professor

Working at the nexus of therapeutic ultrasound, advanced imaging, and tumor immunology to design and deploy precision cancer immunotherapy paradigms.

Faculty Profile

BME Joint Faculty in Cancer Applications

Mark Kester, PhD

Mark Kester, PhD

Professor of Pharmacology, NanoSTAR Director

Developing innovative nanotechnologies for targeted drug delivery in cancer and cardiovascular diseases; pioneered the use of sphingolipids as therapeutics.

Faculty Profile
Nathan Sheffield, PhD

Nathan Sheffield, PhD

Assistant Professor of Public Health Sciences

Using computation to ask and answer biological questions, specifically how DNA encodes regulatory networks that enable cellular differentiation?

Sheffield Lab
Mark Williams, PhD

Professor of Radiology and Medical Imaging

Novel medical imaging systems to be used for early detection and characterization of disease, and for guiding and assessing therapy.

Faculty Profile
Chongzhi Zang, PhD

Chongzhi Zang, PhD

Assistant Professor of Public Health Sciences

Algorithm development for high-throughput genomic data analytics and integrative modeling of gene regulatory networks in mammalian cell systems.

Faculty Profile

More about Cancer Research at UVA

UVA Cancer Center

UVA Cancer Center

A National Cancer Institute (NCI)-designated cancer center

Cancer cell signaling | Molecular genetics and epigenetics | Chemical and structural biology | Immunology and immunotherapy | Women’s oncology | Cancer control and population health.

Cancer Center Website

Sepideh Dolatshahi at her microscope in the lab — Sepideh Dolatshahi, Ph.D.

Our newest assistant professor on why UVA is a great place to start a lab focused on systems immunology.

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Related:

Related:

Cancer

BME Primary Faculty in this Area

Professor

Associate Professor

Founding Dean of the School of Data Science and Professor of BME

Assistant Professor

Assistant Professor

Professor

Professor

Professor

Associate Professor

Associate Professor

Professor

Professor

Assistant Professor

BME Joint Faculty in Cancer Applications

Professor of Pharmacology, NanoSTAR Director

Assistant Professor of Public Health Sciences

Professor of Radiology and Medical Imaging

Assistant Professor of Public Health Sciences

More about Cancer Research at UVA

A National Cancer Institute (NCI)-designated cancer center

Sepideh Dolatshahi, Ph.D.