Fibrosis

Thomas Barker explores and therapeutically exploits the fundamental links between fibroblast adaptation to their physical and biochemical microenvironment and their myofibroblastic differentiation during tissue repair, fibrosis and cancer.

The Caliari Lab designs, synthesizes, and characterizes new biomaterials to explore the dynamic interplay between cells and their microenvironment, applying these platforms to address fundamental human health challenges in understanding disease and engineering tissues.

George Joseph Christ, Ph.D., develops basic and translational tissue engineering and regenerative medicine approaches to organ and tissue repair, reconstruction and replacement, with a focus on the musculoskeletal system, vasculature and lower urinary tract. Dr. Christ is an internationally recognized expert in muscle physiology.

Dr. Epstein is recognized for his contributions to the field of cardiac magnetic resonance imaging. He has been a world leader in advancing MRI myocardial strain imaging by developing and applying the cine DENSE (displacement encoding using stimulated echoes) MRI method.

Donald Griffin improves clinical translation of acellular and cellular therapies through enhanced hydrogel-tissue integration, specifically focusing on the development of passive and active instructional microenvironments using microscale building blocks.

Shayn Peirce-Cottler develops computational models and combines them with wet lab experiments and machine learning to study how tissues heal after injury and to develop new therapies for inducing tissue regeneration.

Jeff Saucerman, PhD, Professor of Biomedical Engineering, combines computational models and high-throughput experiments to discover molecular networks and drugs that control cardiac remodeling.