Cardiovascular Disease
Despite recent advances, cardiovascular disease remains the leading cause of death in the world.
UVA biomedical engineers are developing the next generation of technologies to diagnose and treat cardiovascular disease through multiscale computational modeling, high-throughput discovery platforms, multimodal biomedical imaging, and targeted delivery of regenerative therapeutics.
Primary Faculty in Cardiovascular Disease Application Areas
Mete Civelek
Frederick H. Epstein
Dr. Epstein is recognized for his contributions to the field of cardiac magnetic resonance imaging. He has been a world leader in advancing MRI myocardial strain imaging by developing and applying the cine DENSE (displacement encoding using stimulated echoes) MRI method.
Brent A. French
Brent A. French combines advanced methods of targeted drug and gene delivery with biomedical imaging in vivo to explore novel targets and treatment strategies in cardiovascular disease. Research interests of the Molecular Bioengineering Lab focus on developing new, more effective strategies for treating and preventing human disease.
Brian P. Helmke
Brian Helmke researches the relationship between cell mechanics and cell function using new tools in materials science and molecular biology, with a focus on cardiovascular disease. His laboratory employs a multidisciplinary biomedical engineering approach to understand the relationship between intracellular mechanics and cell function.
Christopher B. Highley
Christopher Highley develops materials and fabrication technologies to enable the design and construction of complex cellular and material systems, with the goal of addressing fundamental and translational problems in biomedicine.
John A. Hossack
John A. Hossack develops ultrasound imaging approaches for cardiovascular disease, including mouse heart imaging, catheter-based imaging and drug delivery, and molecular imaging for diagnosing stroke risk. He obtained B.Eng. and Ph.D. degrees in Electrical and Electronic Engineering, University of Strathclyde and his postdoc at Stanford University.
Craig H. Meyer
Jeff Saucerman
Jeff Saucerman, PhD, Professor of Biomedical Engineering, combines computational models and high-throughput experiments to discover molecular networks and drugs that control cardiac remodeling.
Eli Zunder
Eli Zunder analyzes stem cell fate using single cell mass cytometry and high-dimensional modeling of cell lineage trajectories. He received his Ph.D. in Biophysics from UCSF in 2009.
BME Joint Faculty in Cardiovascular Disease Applications
Brian H. Annex
Brian Annex, MD, is board certified in internal medicine, cardiovascular diseases and interventional cardiology. Prior to his arrival at UVA in 2008, Dr. Annex served as professor of medicine in the Division of Cardiovascular Medicine at Duke University School of Medicine.
Bijoy Kumar Kundu
Bijoy K. Kundu, PhD, is an Associate Professor in the tenure track in the department of Radiology and Medical Imaging at UVA. The goals of his lab are to develop and optimize quantitative cardiac PET imaging techniques to address the hypothesis of metabolic remodeling in small animal modelsof myocardial injury and type 2 diabetes.
Clint Miller
Clint Miller studies the genetic and environmental risk factors for coronary artery disease and other complex cardiovascular diseases using a combination of large-scale multi-omics profiling and genetic and drug perturbations. He is an Assistant Professor in Public Health Sciences and a resident member of the Center for Public Health Genomics.
Paul A. Yates
More about Cardiovascular Disease Research at UVA
Robert M. Berne Cardiovascular Research Center
Supports interdisciplinary research in basic, translational and clinical cardiovascular sciences to better understand the causes of cardiovascular diseases and to pioneer development of new innovative therapies and approaches to prevent or treat them.